Temukunci

Temukunci
Scientific Name	Boesenbergia rotunda (L.) Mansf. Kulturpfl.
Family	Zingiberaceae
Synonyms	Curcuma rotunda L., B. pandurata (Roxb) Schlechtar, Kaempferia pandurata Roxb., Gastrochilus rotundus
Common Name	Fingerroot, Chinese ginger, Chinese key.

{slider= Geographical Distributions}

Habitat: Mixed deciduous and evergreen forest and on limestone hills.

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{slider=Plant Material of Interests}

edible rhizomes, roots, young shoots, medicine and ornamental (1).

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{slider=General Appearances}

Rhizome shape like a bunch of fingers. Small, erect herb, up to 50 cm tall. The rhizomes are bright yellow and strongly aromatic, and they resemble fingers growing from a central point

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{slider=Toxicity test}

Ethanolic extract of B. rotunda in vivo studies showed no significant  changes in body weight of B. rotunda fed rats. All haemotological and histophathologcal parameters used to evaluate the toxicity effect did not show any adverse changes . (Saraithong et al 2010).

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{slider=Pharmacology}

Hepatoprotective Effects

BR rhizome ethanolic extract treatment improved liver histopathology, immunohistochemistry, biochemistry, triggered apoptosis, and inhibitied cytokines, extracellular matrix proteins and hepatocytes proliferation (Salama SM et al 2013).

Antibacterial Activity

Antibacterial activity, in term of MIC, MBC and killing-time curve of methanolic extract of Boesenbergia rotunda have been tested against a standard E. coli ATCC 25922 and two E. coli isolated from milk products using Clinical and Laboratory Standard Institute (CLSI) methods. The results show that B. rotunda extract was susceptible to all E. coli strains. The MIC and MBC values of B. rotunda extract against E. coli ranged 0.019 mg/mL 2.5 mg/mL and 0.039 mg/mL – 5.0 μg/mL, respectively. Killing-time curves were constructed at concentrations of 0x MIC, 1/2x MIC, 1x MIC, and 2x MIC. All E. coli strains can be killed with concentration of 2x MIC after 2 hours. The results show that B. rotunda extract has potential antibacterial activity against E. Coli(Zainin et al., 2013).

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{slider=Reference}

Salama S.M., M.A. Abdulla, A.S. AlRashdi & A. H. A. Hadi (2013). Mechanism of Hepatoprotective Effect of Boesenbergia rotunda in Thioacetamide induced Liver Damage in Rats. Evidence Based Complementary and Alternative Medicine. Vol  Article ID 157456, 13 pg http://www.hindawi.com/journals/ecam/2013/157456/

Saraithong P., Saenphet S., Saenphet K. Safety evaluation of ethanol extracts from Boesenbergia rotunda (L.) mansf. In male rats. Trends Research in Science and Technology. 2010;2(1):19-22.

Charoensin S., et al . Toxicological and clastogenic evaluation of pinocembrin and pinostrobin siolated from Boesenbergia pandurata in Wistar rats. Thai Journal of Toxicology 2010;25 (1):29-40.

Chong T.E., L.Y. Kee, C.C. Fei, H.C. Han, W.S. Ming, C.T. Li Ping, F.G. Teck, N. Khalid, N. Abd Rahman, S.A. Karsani, S. Othman, R. Othman & R. Yusof. (2012). Boesenbergia rotunda: From Ethnomedicine to Drug Discovery. Evid Based Complement Alternat Med http://www.ncbi.nlm.nih.gov/pmc/ articles/PMC3519102/

Zainin, N.S., Lau KY., Zakaria M., Son R., Abdull Razis. AF. & Rukayadi Y. (2013). Antibacterial activity of Boesenbergia rotunda (L) Mansf. A. extract against Escherichia coli. International Food Research Journal 20 (6): 3319-3323.http://www.ifrj.upm.edu.my/

References: http://www.kew.org/plants-fungi/Boesenbergia-rotunda.htm (1)

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