Rumput Cina

Rumput Cina
Scientific Name	Murdannia bracteata (C.B. Clarke)
Family	Commelinaceae
Synonyms	Aneilema bracteatum, Aneilema kuntzei

{slider=Geographical Distributions}

Indo-china Peninsula

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{slider=General Appearances}

Herbs perennial. Roots fibrous, o.5-1 mm in diam. Rhizemes horizontalStem very short, creeping, ascending apically, 20-60 cm.

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{slider=Chemical Contents}

Hydroxybutenolides such as bracteanolide A and bracteanolide B and isovitexin.

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{slider=Traditional Uses}

Treatment for the kidney and liver, including inflammation and cancer. Trat hapatitis, stomatitis, pneumonia, nephritis.

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{slider=Pharmacology}

Hepatoprotective activity

MB possessed potential antioxidant, lipid peroxidation inhibition and free radical scavenging activities. Pretreatment of rats with MB (500 mg/kg and 1000 mg/kg per os) before induction of CCl₄-induced hepatotoxicity showed a dose-dependent reduction in the necrotic changes in hepatic tissue. The increases in plasma malondialdehyde level, serum alanine transaminase and aspartate transaminase activities were also significantly inhibited by MB. The total phenolic content of MB determined using Folin-Ciocalteu assay was found to be 10%. The results of the present study indicated that the hepatoprotective effect of MB is most likely due to its antioxidant and free radical scavenging properties (Yam M.F. et al 2010).

Inducible Nitric Oxide synthase (iNOS) effects

iNOS inhibitory effect of bracteanolide  could be potentially developed as a selective inhibitor for iNOS.

Hydroxybutenolides such as bracteanolide A and bracteanolide B and isovitexin inhibited nitric oxide production. Bracteanolide A significantly inhibited NO production, which is associated with its suppression on iNOS induction in a concentration-dependent manner, with an IC₅₀ of 33.27 ± 0.86 uM. Wang G.J et al (2007)

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{slider=Reference}

Wang G.J., S.M Chen , W.C. Chen, Y.M. Chang and T.H. Lee (2007). Selective inducible nitirc oxide synthase suppression by new bracteanolides from Murdannia bracteata. Journal of Ethnopharmacology 112 Pg 221-227.

Yam M.F. et al (2010) Antioxidant and Hepatoprotective Effects of Murdannia bracteata Methanol Extract Journal of Acupuncture and Meridian Studies Vol 3 (3) 197-202.

http://www.efloras.org/florataxon.aspx?flora_id=2&taxon_id=240001471

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