Recent Publications

Organoid Technology for Disease Modelling and Personalized Treatment. Book (2022).
Yahaya, B.H.

Lung Organoid: Innovative Technology for Respiratory Disease Modelling (2022).
Abdul Halim, N.S.S., Shaffie, S.A.C., Ab Patar, M.N.A., Yahaya, B.H.
In: Yahaya, B.H. (eds) Organoid Technology for Disease Modelling and Personalized Treatment . Stem Cell Biology and Regenerative Medicine, vol 71. Humana, Cham. doi: https://doi.org/10.1007/978-3-030-93056-1_3

Biomaterials in Organoid Development (2022).
Abdul Samat, A., Yahaya, B.H.
In: Yahaya, B.H. (eds) Organoid Technology for Disease Modelling and Personalized Treatment . Stem Cell Biology and Regenerative Medicine, vol 71. Humana, Cham. doi: https://doi.org/10.1007/978-3-030-93056-1_8

Ethical Implications on Organoid (2022).
Yahaya, B.H., Shaffie, S.A.C., Sasongko, T.H.
In: Yahaya, B.H. (eds) Organoid Technology for Disease Modelling and Personalized Treatment . Stem Cell Biology and Regenerative Medicine, vol 71. Humana, Cham. doi: https://doi.org/10.1007/978-3-030-93056-1_10

Therapeutic Potential of Adipose-derived Stem Cells in the Treatment of Pulmonary Diseases (2022).
Abdul Halim, N.S.S., Yahaya, B.H., Lian, J.
CSCR 17, 103–112. doi: https://doi.org/10.2174/1574888X16666210812145202

Isolation and Characterization of Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells (2022).
Ridzuan, N., Widera, D., Yahaya, B.H.
In: Kannan, N., Beer, P. (eds) Stem Cell Assays. Methods in Molecular Biology, vol 2429. Humana, New York, NY. doi: https://doi.org/10.1007/978-1-0716-1979-7_18

The Enrichment of Breast Cancer Stem Cells from MCF7 Breast Cancer Cell Line Using Spheroid Culture Technique (2022).
Ishtiah, A.A., Yahaya, B.H.
In: Kannan, N., Beer, P. (eds) Stem Cell Assays. Methods in Molecular Biology, vol 2429. Humana, New York, NY. doi: https://doi.org/10.1007/978-1-0716-1979-7_32

Nonfreezing Low Temperature Maintains the Viability of Menstrual Blood–Derived Endometrial Stem Cells Under Oxygen–Glucose Deprivation Through the Sustained Release
of Autophagy-Produced Energy (2022).
Chen, T., Zhang, S., Jin, H., Fu, X., Shang, L., Lu, Y., Sun, Y., Hisham Yahaya, B., Liu, Y., Lin, J.
Cell Transplant 31, 096368972210869.
doi: https://doi.org/10.1177/09636897221086971

Tissue Engineering for Tracheal Replacement: Strategies and Challenges (2022).
Samat, A.A., Hamid, Z.A.A., Mariatti Jaafar @ Mustapha., Yahaya, B.H.
In: Advances in Experimental Medicine and Biology(). Springer, Cham.
doi: https://doi.org/10.1007/5584_2022_707

Therapeutic effects of menstrual blood-derived endometrial stem cells on mouse models of streptozotocin-induced type 1 diabetes (2022).
Sun YL, Shang LR, Liu RH, Li XY, Zhang SH, Ren YK, Fu K, Cheng HB, Yahaya BH, Liu YL, Lin JT.
World J Stem Cells. 2022 Jan 26;14(1):104-116. doi: 10.4252/wjsc.v14.i1.104. PMID: 35126831; PMCID: PMC8788184.

Preliminary study on reactive compatibilisation of poly-lactic acid with maleic anhydride and dicumyl peroxide for fabrication of 3D printed filaments (2020).
Samat, A.A., Hamid, Z.A.A., Jaafar, M., Yahaya, B.H.
Presented at the 3RD INTERNATIONAL POSTGRADUATE CONFERENCE ON MATERIALS, MINERALS & POLYMER (MAMIP) 2019, Penang, Malaysia, p. 020014. doi: https://doi.org/10.1063/5.0016426

Production and differential activity of recombinant human wild-type G6PD and G6PDViangchan (2020).
Vengidasan, Lelamekala, Yunus, Muhammad Amir, Yusoff, Narazah Mohd, Yahaya, Badrul Hisham and Ismail, Ida Shazrina. Asian Biomedicine, vol.14, no.4, 2020, pp.159-167. doi: https://doi.org/10.1515/abm-2020-0023

Osteoblasts migration, attachment and human bone marrow-mesenchymal stem cells osteogenic differentiation towards surface engineered and growth factors conjugated poly(lactic acid) microspheres (2020).
Mohd Sabee, M.M.S., Kamalaldin, N.A., Yahaya, B.H. & Abdul Hamid, Z.A..
J Mater Sci: Mater Med 31, 45 (2020). doi: https://doi.org/10.1007/s10856-020-06380-y

Acute Lung Injury: Disease Modelling and the Therapeutic Potential of Stem Cells (2020).
Lian, J., Lin, J., Zakaria, N., Yahaya, B.H.
In: Turksen, K. (eds) Cell Biology and Translational Medicine, Volume 10. Advances in Experimental Medicine and Biology(), vol 1298. Springer, Cham. doi: https://doi.org/10.1007/5584_2020_538

Adipose-Derived Mesenchymal Stem Cells Promote Growth and Migration of Lung Adenocarcinoma Cancer Cells (2020).
Zakaria, N., Yahaya, B.H.
In: Pham, P.V. (eds) Cancer Biology and Advances in Treatment. Advances in Experimental Medicine and Biology(), vol 1292. Springer, Cham. https://doi.org/10.1007/5584_2019_464

Transcriptomic Profiles of MV4-11 and Kasumi 1 Acute Myeloid Leukemia Cell Lines Modulated by Epigenetic Modifiers Trichostatin A and 5-Azacytidine (2020).
Asmaa MJS, Al-Jamal HA, Hussein AR, Yahaya BH, Hassan R, Hussain FA, Shamsuddin S, Johan MF.
Int J Hematol Oncol Stem Cell Res. 2020 Jan 1;14(1):72-92. PMID: 32337016; PMCID: PMC7167603.

Anti-Coagulation Activities of Malaysian Mikania cordata Leaves (2019).
Wan Norshazwani Wan Shafee, Nur Yuzaiza Yusof, Hafizuddin Mohamed Fauzi, Lim Vuanghao, Nurulain Atikah Kamalaldin, Badrul Hisham Yahaya. International Journal of Peptide Research and Therapeutics 25 (3), 941-949

Aerosolised mesenchymal stem cells expressing angiopoietin-1 enhances airway repair (2019).
NSS Halim, ES Ch’ng, E Kardia, SA Ali, R Radzi, BH Yahaya. Stem Cell Rev Rep. 2019 Feb;15(1):112-125. doi: 10.1007/s12015-018-9844-7.

Physico-Mechanical Properties of HA/TCP Pellets and Their Three-Dimensional Biological Evaluation In Vitro (2019).
M Jaafar, SI Zubairi, BH Yahaya. Adv Exp Med Biol. 2019;1084:1-15. doi: 10.1007/5584_2017_130

Secretome of Mesenchymal Stem Cells and its Impact on Chronic Obstructive Pulmonary Disease (2019).
N Ridzuan, D Widera, BH Yahaya. Stem Cell Transplantation for Autoimmune Diseases and Inflammation, 139-157

Effect of the calcination temperature on the properties of natural hydroxyapatite derived from chicken bone wastes (2019).
SL Bee, M Mariatti, N Ahmad, BH Yahaya, ZAA Hamid
Materials Today: Proceedings 16, 1876-1885

Conditioned Medium of Human Menstrual Blood-Derived Endometrial Stem Cells Protects Against MPP+-Induced Neurotoxicity In Vitro (2019).
H Li, BH Yahaya, N Mohd Yusoff, JT Lin. Frontiers in molecular neuroscience 12, 80

The effect of mesenchymal stem cell-secreted factors on airway epithelial repair (2018).
NSSA Halim, WM Aizat, BH Yahaya. Regenerative medicine 14 (1), 15-31

Surface Roughness, Hydrophilicity and Encapsulation Efficiency of Gentamicin Loaded Surface Engineered PLA Microspheres (2018).
TTT Trang, M Jaafar, BH Yahaya, M Kawashita, NXT Tram, ZAA Hamid. Journal of Physics: Conference Series 1082 (1), 012068

Novel triple‑positive markers identified in human non‑small cell lung cancer cell line with chemotherapy-resistant and putative cancer stem cell characteristics (2018).
Nazilah Abdul Satar, Kamal Shaik Fakiruddin, Moon Nian Lim, Pooi Ling Mok, Norashikin Zakaria, Noor Atiqah Fakharuzi, Abd Rahman, Ahmad Zuhairi, Zubaidah Zakaria, Badrul Hisham Yahaya, Puteri Baharuddin. Oncology reports 40 (2), 669-681

Approaches to improve therapeutic efficacy of biodegradable PLA/PLGA microspheres: a review (2018).
SL Bee, ZAA Hamid, M Mariatti, BH Yahaya, K Lim, ST Bee, LT Sin. Polymer Reviews 58 (3), 495-536

An analysis of genetic association in opioid dependence susceptibility (2018).
D Nagaya, Z Zahari, M Saleem, BH Yahaya, SC Tan, NM Yusoff. Journal of clinical pharmacy and therapeutics 43 (1), 80-86

Aerosol‐based airway epithelial cell delivery improves airway regeneration and repair (2018).
E Kardia, ES Ch’ng, BH Yahaya. Journal of tissue engineering and regenerative medicine 12 (2), e995-e1007

Inhibition of NF-κB signaling reduces the stemness characteristics of lung cancer stem cells (2018).
N Zakaria, NM Yusoff, Z Zakaria, D Widera, BH Yahaya. Frontiers in oncology 8

The BRCA1 and BRCA2 Genes in Early-Onset Breast Cancer Patients (2018).
Mohamed Saleem, Mohd Bazli Ghazali, Md Azlan Mohamed Abdul Wahab, Narazah Mohd Yusoff, Hakimah Mahsin, Imran Abdul Khalid, Mohd Nor Gohar Rahman, Badrul Hisham Yahaya. Adv Exp Med Biol. 2018 Apr 24. doi: 10.1007/5584_2018_147. [Epub ahead of print]

The Use of mesenchymal stromal cells in treatment of lung disorders
E Kardia, N Zakaria, NSSA Halim, D Widera, BH Yahaya
Regen Med. 2017 Mar;12(2):203-216. doi: 10.2217/rme-2016-0112. Epub 2017 Feb 17

Aerosol‐based Airway Epithelial Cell Delivery Improves Airway Regeneration and Repair
E Kardia, ES Ch'ng, BH Yahaya
J Tissue Eng Regen Med. 2017 Jan 20. doi: 10.1002/term.2421.

Targeting Lung Cancer Stem Cells: Research and Clinical Impacts
Norashikin Zakaria, Nazilah Abdul Satar, Noor Hanis Abu Halim, Siti Hawa Ngalim, Narazah Mohd Yusoff and Juntang Lin, Badrul Hisham Yahaya
Front. Oncol. 7:80. doi: 10.3389/fonc.2017.00080

Does inhalation of virgin coconut oil accelerates reversal of airway remodelling in an allergic model of asthma?
Nurulain 'Atikah Kamalaldin, Siti Amrah Sulaiman, Rahimi M. Yusop and Badrul Hisham Yahaya
International Journal of Inflammation. Volume 2017 (2017), Article ID 8741851, 11 pages

Physico-mechanical properties of HA/TCP pellets and their three-dimensional biological evaluation in vitro
Nurulain ‘Atikah Kamalaldin, Mariatti Jaafar, Saiful Irwan Zubairi, Badrul Hisham Yahaya
Advances in Experimental Medicine and Biology (In-press)

An analysis of genetic association in opiod dependence susceptibility
Devaki Nagaya, Zalina Zahari, Mohamed Saleem, Badrul Hisham Yahaya, Tan Soo Choon, Narazah Mohd Yusoff
J Clin Pharm Ther. 2017 Jun 27. doi: 10.1111/jcpt.12585.

Stimulatory Secretions of Airway Epithelial Cells Accelerate Early Repair of Tracheal Epithelium. E Kardia, R Mohamed, BH Yahaya. Scientific reports 7, 11732 

Aerosol-based cell delivery as an innovative treatment for lung diseases
BH Yahaya, NSS Abdul Halim, E Kardia
Biomedical Research and Therapy 4 (S), S41-S41

Lung cancer stem cell and its therapeutic potential
BH Yahaya, N Zakaria, NHA Halim, N Satar
Biomedical Research and Therapy 4 (S), S15-S16

Direction of commissural axon projections in different regions of the spinal cord during chicken embryonic development.
H Li, C Yang, NM Yusoff, BH Yahaya, J Lin.
Neuroscience 358, 269-276

Physico-chemical and biological activity of Malaysian channa striatus water extract on human foetal lung cell (IMR-90)
Winnie Ngui Shy Yi, Syazwan Aizad Abdul Mutalib, Badrul Hisham Yahaya and Saiful Zubairi
Front. Bioeng. Biotechnol.  doi: 10.3389/conf.FBIOE.2016.02.00009

Coating and surface treatments enhance scaffold degradation
Nurulain Atikah Kamalaldin, Mohd Meer Saddiq Mohd Sabee, Fadhilah Darus, Mariatti Jaafar, Nurazreena Ahmad, Zuratul Ain Abdul Hamid and Badrul Hisham Yahaya
Front. Bioeng. Biotechnol.  doi: 10.3389/conf.FBIOE.2016.02.00013

Isolation and characterisation of CD166+/EpCAM+ and CD166+/CD44+as markers for cancer stem cells from non-small cell lung cancer of A549
Noor Hanis Abu Halim, Norashikin Zakaria and Badrul Hisham Yahaya
Front. Bioeng. Biotechnol.  doi: 10.3389/conf.FBIOE.2016.02.00007

Jurnal Teknologi: 78: 11–3 (2016) 19–25
Down-Regulation of ALDH1A1 increased expression of carcinogenesis-related genes in non-small cell lung cancer cell line of a549
Noor Hanis Abu Halim, Norashikin Zakaria, Badrul Hisham Yahaya

Jurnal Teknologi: 78: 11–3 (2016) 41–49 |
Proliferative activity of saponin-reducing carica papaya leaves extracts on human lung fibroblast cell (imr90)
Noraziani Zainal Abidin, Hazreen Omar, Anathasia Janam Empungan, Nurulain 'Atikah Kamalaldin, Badrul Hisham Yahaya, Saiful Irwan Zubairi

J. of Biomed. & Clin. Sci. December 2016 Vol 1 (1), 1-8
Regeneration and Repair of Damaged Trachea Epithelium following Brushing-induced Injury in Rabbits
Latahir AZ, Kardia E, Yahaya B

Human non-small cell lung cancer expresses putative cancer stem cell markers and exhibits the transcriptomic profile of multipotent cells
Norashikin Zakaria, Narazah Mohd Yusoff, Zubaidah Zakaria, Moon Nian Lim, Puteri J Noor Baharuddin, Kamal Shaik Fakiruddin, Badrul Yahaya
BMC Cancer. 2015, 15:84
DOI: 10.1186/s12885-015-1086-3
URL: http://www.biomedcentral.com/1471-2407/15/84

Study the Electrical Conductivity of Cross-Linked Polymers Doped with LiClO4
Emad Yousif, Emaad T. B. Al-Tikrity, Mustafa Abdalla, Rahimi M. Yusop, Badrul Hisham Yahaya, Darfizzi Derawi
Int. J. Electrochem. Sci., 10 (2015) 2055 – 2063

Preparation and characterization of HypoGel‐supported Pd nanocatalysts for Suzuki reaction under mild conditions
Kin Hong Liew, Wan Zurina Samad, Norazzizi Nordin, Poh Lee Loh, Joon Ching Juan, Mohd Ambar Yarmo, Badrul Hisham Yahaya, Rahimi M. Yusop
Chinese Journal of Catalysis 36 (2015)

Apoptosis in lung cancer cells induced by virgin cocnut oil
N‘A Kamalaldin, MR Yusop, SA Sulaiman, BH Yahaya
Regenerative Research 4(1) 2015 30-36

DEVELOPMENT OF A RAPID CONTINUOUS FLOW SALT LEACHING KIT FOR FABRICATION OF POLY(3-HYDROXYBUTYRIC ACID-CO-3-HYDROXYVALERATE) (PHBV) POROUS 3-D SCAFFOLD
Syazwan Aizad, Badrul Hisham Yahaya, Saiful Irwan Zubairi
(2015) Jurnal Teknologi 75 (1) pp. 193-199
DOI: http://dx.doi.org/10.11113/jt.v75.3903

GUIDELINES FOR NUCLEIC ACID DETECTION AND ANALYSIS IN HEMATOLOGICAL DISORDERS
ROSLINE HASSAN, AZLAN HUSIN, SARINA SULONG, SURINI YUSOFF, MUHAMMAD FARID JOHAN,BADRUL HISHAM YAHAYA, CY ANG,SELAMAH GHAZALI AND CHEONG SOON KENG
Malaysian J Pathol 2015; 37(2) : 165 – 173

Curcumin improves the efficacy of cisplatin by targeting cancer stem-like cells through p21 and Cyclin D1-mediated tumour cell inhibition in non-small cell lung cancer (NSCLC) cell lines
Puteri Baharuddin, Kamal Shaik Fakiruddin, Nazilah Satar, Norashikin Zakaria, Moon Nian Lim, Narazah Mohd Yusoff, Zubaidah Zakaria, Badrul Hisham Yahaya
Oncol Rep. 2016 Jan;35(1):13-25. doi: 10.3892/or.2015.4371.

Multiplex amplification refractory mutation system (MARMS) for the detection of β-globin gene mutations among the transfusion-dependent β-thalassemia Malay patients in Kelantan, Northeast of Peninsular Malaysia.
Hanafi S, Hassan R, Bahar R, Abdullah WZ, Johan MF, Rashid ND, Azman NF, Nasir A, Hassan S, Ahmad R, Othman A, Ibrahim MI, Sukeri S, Sulong S, Yusoff S, Mohamad NS,
Hussein A, Hassan R, Yusoff N, Yahaya BH, Ismail E, Yussof NK, Salleh S, Zilfalil BA.
Am J Blood Res. 2014 Sep 5;4(1):33-40. eCollection 2014.

Int J Mol Sci. 2014 Aug 26;15(9):15044-60. doi: 10.3390/ijms150915044.
A comparative study of non-viral gene delivery techniques to human adipose-derived mesenchymal stem cell.
Halim N1, Fakiruddin KS, Ali SA, Yahaya BH.

Int J Mol Sci. 2014 May 19;15(5):8835-45. doi: 10.3390/ijms15058835.
Molecular characterization of α- and β-thalassaemia among Malay patients.
Yatim NF, Rahim MA, Menon K, Al-Hassan FM, Ahmad R, Manocha AB, Saleem M, Yahaya BH.

BMC Complement Altern Med. 2014 May 29;14(1):176. doi: 10.1186/1472-6882-14-176.
Inhalation of honey reduces airway inflammation and histopathological changes in a rabbit model of ovalbumin-induced chronic asthma.
Kamaruzaman NA, Sulaiman SA, Kaur G, Yahaya B.

Madu alternatif rawat asma: Saintis USM temui cara kurangkan penyakit kronik [Ruangan Rencana Berita Harian (NSTP): 4 Januari 2014]

Honey-based inhaler for asthma

Badrul Hisham Y, Aliza MY, Zaiton Y, Puteri JN, Norsiah MD, Hishamshah I, Zubaidah Z. Chimerism analysis in patients with acute lymphoblastic leukaemia after allogeneic haematopoietic stem cell transplantation: Malaysian Journal of Biochemistry and Molecular Biology (2007) 15(2), 84-87, 2007, 15, , 84-87

Y. Badrul Hisham, H. Rosline, W. M. Wan Maziah, S. Mohammad Ros, B. Abdul Aziz, B. Norsaadah, M. Y. Narazah. Screening for 3435C>T and G2677G>T/A Polymorphisms of Multi-drug Resistance (MDR1) Gene in Malay Patients with Leukemia: Malaysian Journal of Biochemistry and Molecular Biology (2006) 14, pg 18-24., 2006, 14, , 18-24

Y. Badrul Hisham, H. Rosline, W. M. Wan Maziah, S. Mohammad Ros, B. Abdul Aziz, B. Norsaadah, M. Y. Narazah. Rapid Screening for C3435T Polymorphism in Exon 26 of the Multi-drug Resistance (MDR1) Abstract published in The Malaysian Journal of Medical Sciences, Vol. 12, Suppl. 1, 2005, pg 61