Summary of Research
Dr. Yahaya’s group interest is in understanding of the mechanisms that underlay lung disease in the context of pre-clinical setting prior to be evaluated in a clinical application. For this purpose, his group has developed a rabbit as an animal model system to focus on understanding the molecular and cellular mechanisms underlying airway epithelial regeneration and repair.
His current research works involve basic understanding on pathophysiological changes of the airway during injury and repair, application of stem cell therapy for acute and chronic lung diseases using rabbit as a model, preclinical evaluation of stem cell-based gene therapy treatment for ANGPT1 gene in chronic lung disease, understanding transcriptomic composition of lung cancer stem cells, and the effect of curcumin in chemo-resistant and metastasise of lung cancer stem cell during lung cancer development and progression using both in vivo and in vitro model systems. Dr. Yahaya expertise are in human genetic studies, stem cell, cell-based therapy, primary cell culture, animal model for lung injury and repair, microarray and bioinformatics for gene expression analysis.
Dr. Yahaya has currently received research grants from various funding bodies such as the Universiti Sains Malaysia (Short Term and Research University Grant Schemes), the Ministry of Science, Technology and Innovation (MOSTI) of Malaysia as well as the research grant from the National Institute of Health/Ministry of Health, Malaysia, where he acts as a Principal Investigator.
As a principal investigator, Dr. Yahaya has currently received research grants from various funding bodies such as the Universiti Sains Malaysia (Short Term and Research University Grant Schemes), the Ministry of Science, Technology and Innovation (MOSTI) of Malaysia (E-Science Fund), the National Institute of Health/Ministry of Health (NIH/MOH), Malaysia, the Ministry of Higher Education, Malaysia (the Transdisciplinary Research Grant Scheme (TRGS) and the Fundamental Research Grant Scheme (FRGS)) to work on various aspect of pulmonary researches.