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Research Projects

 

Research Grant:

PI, Co-I, Grant Title, Total Amount, Duration

a.

International

i.

Principal Investigator

1.

Badrul Hisham Bin Yahaya, -, Projek Kerjasama Bakat Antarabangsa Tahun 2014 (Penyelidikan dan Penggunaan Aerosol dalam Pencantuman Sel-sel 
Stem bagi Rawatan Paru-paru), RM39,337.63, 01/07/2014-31/12/2014

2. 

Badrul Hisham Bin Yahaya, -, 3D-Printed Tracheal Scaffold as an Alternative Source for Trachea Replacement, USD 5000.00 (Nippon Sheet Glass Foundation, Japan)

ii.

Co-Researcher

1.

Zuratul Ain Binti Abdul Hamid, Badrul Hisham Bin Yahaya, Mariatti Binti Jaafar@ Mustapha, PROF DR. MASAKAZU KAWASHITA , TRAN THI THU TRANG, 
The Development of PLA Microspheres for Drug Delivery Application, RM17,452.00, 01/10/2016-30/09/2018

b.

National

i.

Principal Investigator

1.

Badrul Hisham Bin Yahaya, Kumitaa A/p Theva Das, The roles of ALDH1A1 and RARB1 in regulating the tumorigenicity of the non-small cell lung cancer 
(NSCLC) stem cells , RM147,200.00, 02/11/2015-01/11/2018

2.

Badrul Hisham Bin Yahaya, DR SAIFUL IRWAN ZUBAIRI, Masrina Binti Mohd Nadzir, MUHAMMAD RAHIMI YUSOP, THE EFFECT OF BIOACTIVE AND 
BIORESORBABLE CERAMIC/POLYMER LAYER SCAFFOLD ON BONE-DERIVED PROGENITOR AND STEM CELL BEHAVIOURS, 
RM170,468.00, 01/10/2014-30/09/2017

3.

Badrul Hisham Bin Yahaya, -, Development of in vitro Model System and Migration Pathways on Chemo-Resistant Cancer Stem Cell-Induced Lung 
Cancer (NMRR-12-868-13492), RM281,000.00, 01/09/2012-31/08/2014

4.

Badrul Hisham Bin Yahaya, Azlina Binti Ahmad, Siti Amrah Bte Sulaiman, Honey-Based Inhaler And Its Regenerative Potential In Animal Model Of Asthma,
RM257,000.00, 01/04/2012-30/06/2014

5.

Badrul Hisham Bin Yahaya, -, Effect of TERT & TERC gene expressions in regulating the development and progression of acute lymphoblastic leukemics cancer
cells, RM140,000.00, 20/10/2011-31/12/2012

6.

Badrul Hisham Bin Yahaya, -, Preclinical efficacy of MSC transplantation in an experimental model of liver cirrhosis, 
RM250,000.00, 01/10/2011-30/09/2013

ii.

Co-Researcher

1.

Yanny Marliana Binti Baba Ismail, Ahmad Fauzi Bin Mohd Noor, Badrul Hisham Bin Yahaya, Siti Mardhiana Binti Mohamad, Understanding the mechanism of
multi-doping ions in Carbonated Hydroxyapatite (CHA) 
Scaffolds to induce rapid bone formation, RM106,000.00, 15/08/2017-14/08/2020

2.

Kumitaa A/p Theva Das, Badrul Hisham Bin Yahaya, Ida Shazrina Binti Ismail, Yahya Bin Mat Arip, Using zinc finger nuclease (ZFN) to study the effects of 
indels on HIV-1 replication and virulence in pNL4-3, an HIV model system,RM145,000.00, 01/12/2014-31/05/2018

3.

Zuratul Ain Binti Abdul Hamid, Badrul Hisham Bin Yahaya, Mariatti Binti Jaafar @ Mustapha, Zulkifli Bin Ahmad, Synthesis of folate molecules on Poly(lactide) (PLA) Nanoparticles by Bioconjugation Chemistry, RM139,000.00, 01/07/2014-31/12/2017

4.

Masrina Binti Mohd Nadzir, Abdul Rahman Bin Mohamed, Badrul Hisham Bin Yahaya, MEE-HAE KIM, Characterization And Efficacy Evaluation Of Modified Collagen Hydrogel With Tethered Nanocurcumin, RM68,500.00, 01/12/2013-31/05/2017

c.

University

i.

Principal Investigator

1.

Badrul Hisham Bin Yahaya, DR. DARIUS WIDERA, DR. MITSURU MORIMOTO, Shaharum Bin Shamsuddin, The Anti-senescence Effects of Mesenchymal Stem Cells (MSC)-Derived Extracellular Vesicles (Evs) on COPD, RM150,000.00, 01/03/2017-29/02/2020

2.

Badrul Hisham Bin Yahaya, -, Celik Genetik, Terokai Stem Cell, RM12,000.00, 01/09/2014-31/08/2015

3.

Badrul Hisham Bin Yahaya, EGI KARDIA, Md Azlan Bin Mohamad Abdul Wahab, NAZILAH BINTI ABDUL SATAR, NORASHIKIN BINTI ZAKARIA, NUR SHUHAIDATUL SARMIZA BINTI ABDUL HALIM, NURULAIN 'ATIKAH BINTI KAMALALDIN, Shahirah Akmar Binti Hashin, CELIK GENETIK, TEROKAI SEL STEM , RM12,000.00, 01/08/2014-31/07/2015

4.

Badrul Hisham Bin Yahaya, Hasnan Bin Jaafar, Rosline Bt Hassan, Shaharum Bin Shamsuddin, Zubaidah Binti Zakaria, ZUBAIDAH ZAKARIA. Preclinical Efficacy of Cell-Based Gene Transfer of Mesenchymal Stem Cells Overexpressing Angiopoietin-1 in an Experimental Model of Chronic Lung Disease , RM222,450.00, 15/07/2012-31/10/2016

5.

Badrul Hisham Bin Yahaya, Hasnan Bin Jaafar, Narazah Binti Mohd Yusoff, Zubaidah Binti Zakaria, Understanding Transcriptomic Compositions Of Lung Cancer Stem Cell And The Effect Of Cancer Stem Cell In Lung Cancer Development And Progression Using Both In vivo And In vitro Model Systems, RM248,184.00, 15/07/2012-14/10/2015

6.

Badrul Hisham Bin Yahaya, Zubaidah Binti Zakaria, Shaharum Bin Shamsuddin, Establishment of Aerosol-based Cell Delivery Technique to Study the Effect of Airway Epithelial Stem Cell-Like Cells Regeneration in Animal Models of Acute Lung Injury, RM39,975.00, 15/01/2012-14/07/2014

7.

Badrul Hisham Bin Yahaya, -, Analysis of Pathophysiological Changes of the Airway Epithelium During Regeneration and Repair Following Tracheal Brushing in Rabbit , RM39,700.00, 01/03/2011-28/02/2013

8.

Badrul Hisham Bin Yahaya, -, Blood coagulation factor activity of Mikania cordata leaves , RM5,000.00, 09/11/2010-08/05/2012

ii.

Co-Researcher

1.

Abdul Rahim Bin Hussein, Azlan Bin Husin, Badrul Hisham Bin Yahaya, GOH AI SIM, Muhammad Farid Bin Johan, NORIA ABDUL MUTALIB, Shafini Bt. Mohamed Yusoff, SINARI SALLEH, The Effects of NPM1, FLT3 and CEBPA Gene Mutations in Adult Patients with Acute Myeloid Leukaemia (AML), RM40,434.20, 01/04/2016-31/03/2018

2.

Shaharum Bin Shamsuddin, Azalina Zainuddin, Badrul Hisham Bin YahayaDR. CHOI SY BING, Eugene Ong Boon Beng, Gam Lay Harn, Lai Ngit Shin, Liong Min Tze, Oon Chern Ein, PROF. KUNIYA ABE, Biochemical Characterization of Sirtuin (1&6) and Amyloid Protein Pathway in Alzheimer's Cellular Model SHSY5Y , RM250,000.00, 01/08/2015-31/07/2020

3.

Fitreena Anis Binti Amran, Badrul Hisham Bin Yahaya, IMRAN ABDUL KHALID, Mohd Nor Bin Gohar Rahman, The Relationship of P53 Gene Mutation with Clinicopathological Characteristic In Breast Cancer, RM40,500.00, 15/12/2014-14/09/2017

4.

Zilfalil Bin Alwi, Adil Bin Hussein, AMIR FEISAL MERICAN, Azizah Binti Othman, Badrul Hisham Bin Yahaya, ELIZABETH GEORGE, ENDOM ISMAIL, HISHAMSHAH MOHD IBRAHIM, Liza Sharmini Bt. Ahmad Tajudin, M.L. SAOVAROS SVASTI, Md Azman Bin Pkm Seeni Mohamed, Mohd Ezane Bin Aziz, Mohd Ismail Bin Ibrahim, Mohd Nazalan Bin Mohd Najimudin, Mohd Syakir Bin Mohd Rosdi, Muhammad Farid Bin Johan, Narazah Binti Mohd Yusoff, Norsarwany Binti Mohamad, ONN HAJI HASHIM, PUTERI SHAFINAZ AKMAR, RAHIMAH AHMAD , Rosline Bt Hassan, Rosnah Binti Bahar, Rosni Binti Abdullah @ Mustafa, Rozita Hassan, Sakinah Binti Harith, Sarina Sulong, SHEKHAR KRISHNAN, Surianti Binti Sukeri, Surini Binti Yusoff, SUTHAT FUCHAROEN, THONG MEOW KEONG, Wan Zaidah Abdullah, ZARINA ABDUL LATIFF, ZUBAIDAH ZAKARIA, Targeted Genetic Modifiers And Socio-Environmental Influences Contributing To Phenotypic Heterogeneity Of Hb E/ B Thalassemia , RM867,150.00, 01/02/2013-31/07/2016

5.

Muzaimi Mustapha, Badrul Hisham Bin Yahaya, Habibah Binti A Wahab, Sarina Sulong, Teguh Haryo Sasongko, Zabidi Azhar Bin Husin @ Mohd Hussin, A Study on Isodiospyrin Putative Inhibitory actions against exonic splicing enhancers of dystrophin gene exon skipping in Duchenne Muscular Dystrophy, RM223,150.00, 15/07/2012-14/04/2016

6.

Azlina Binti Ahmad, Badrul Hisham Bin Yahaya, Suzina Bt. Sheikh Abdul Hamid, T. P. Kannan, Gene Expression Analysis of Aquaporin3 During Keratinocytes Differentiation from Stem Cells of Human Amniotic Membrane, RM40,000.00, 01/06/2012-30/11/2014

7.

Muhammad Farid Bin Johan, Abdul Rahim Bin Hussein, Azlan Bin Husin, Badrul Hisham Bin Yahaya, Rosline Bt Hassan, Shaharum Bin Shamsuddin, Identification of Differentially Expressed Genes & Epigenetic Inactivation Profiling of Various Cytogenetic Rearragements in Primary AML Cell Lines, RM240,662.25, 01/12/2011-30/11/2015

8.

Narazah Binti Mohd Yusoff, Badrul Hisham Bin Yahaya, COLLEN MASIMIREMBWA, ENDOM ISMAIL , Harmy Mohamed Yusoff, MOHD HUSSAIN HABIL, MOHD KHAFIDZ ISHAK , Nasir Bin Mohamad, Nur Fadhlina Binti Musa, Rahmat Bin Awang, Surini Binti Yusoff, ZULLIES IKAWATI, Development Of Ethno-pharmacogenetics Relatedness And Personalised Medicine, RM693,438.69, 01/07/2011-31/03/2016