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Keynote Speakers

 

Professor Ian Goodfellow

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Professor Ian Goodfellow is Professor of Virology and currently the acting deputy head of the Department of Pathology at the University of Cambridge. He studied microbiology and virology as an undergraduate at the University of Warwick, before undertaking a PhD at the University of Nottingham in bacterial genetics. His research career in virology started in 1996 as a postdoctoral research fellow at the University of Reading studying picornavirus-host interactions. This continued at the University of Glasgow until 2003 when he established his own research group at the University of Reading, with the help of a Wellcome Trust career development fellowship, focusing on the study of a family of caliciviruses. Since then he has worked at Imperial College London before moving to the University of Cambridge in October 2012. Research in Professor Goodfellow’s lab is primarily supported by a Wellcome Senior fellowship but he also currently holds grants from the BBSRC and Innovate UK.

His research to date has largely focused on the mechanisms of RNA virus replication and pathogenesis as well as the identification of control measures for the prevention or treatment of infections. He founded the use of reverse genetics to study the molecular basis of norovirus pathogenesis, developing the first infectious reverse genetics system for any norovirus. He has also characterized the role of viral RNA structures in the norovirus life cycle and identified host cell factors that contribute to both virus replication in cell culture but also pathogenesis in the natural host. He has recently expanded his interests to understand the virus-host interface in veterinary pathogens including viral zoonosis. During the 2014-16 Ebola virus epidemic, Professor Goodfellow was involved in the establishment and running of one of the first diagnostic facilities in Sierra Leone in the Bombali district of Sierra Leone. Working with Public Health England, Professor Goodfellow led a team of scientists who establish Ebola virus diagnostic at the Mateneh Ebola Treatment Centre in Makeni. In April 2015, Professor Goodfellow obtained funding from the Wellcome Trust to establish real-time sequencing capacity in a tent next to the diagnostic lab in the treatment centre. Professor Goodfellow and his team established a robust sequencing workflow and were able to sequence clinical samples within 24 hours of isolation from the patient. Working closely with the WHO, Public Health England, the Sierra Leonean Ministry of Health, the US CDC, Professor Goodfellow was heavily involved in the provision of sequencing for use in real-time epidemiological tracing/monitoring of Ebola infections in Sierra Leone and (in collaboration with Loman) neighbouring Guinea. Following the end of the epidemic, Professor Goodfellow has established the University of Makeni Infectious Disease Research Laboratory, which now provides in country next generation sequencing and laboratory support to researchers working within Sierra Leone.

 
 

Professor Dale Fisher

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Prof Dale Fisher

MBBS 1986, FRACP 1993, DTM&H 1993

Head, Clinical Director and Senior Consultant, Division of Infectious Diseases

Chair, Infection Control, National University Hospital

Experience:

  • Royal Darwin Hospital, Australia 1992 to 2004
  • National University Hospital, Singapore 2004 till to date

Clinical Interests:   

  • General tropical Infectious Disease
  • Outpatient Parenteral Antibiotic Therapy (OPAT)
  • MRSA control in healthcare settings
  • Outbreak investigations and management (Global and Local)

Awards:  

  • Courage Medal, Courage foundation Singapore March - May'03
  • RACP John Sands Medal for outstanding contribution to College Affairs (May 2006)
  • NUS Yong Loo Lin School of Medicine Faculty Teaching excellence award - 2008 & 2009

Sample Publications:

  1. Cryptococcal meningitis (C. neoformans var gattii) leading to blindness in previously healthy Melanesian adults in Papua New Guinea.  D Lalloo, D Fisher, S Naraqi et al.  Quarterly Journal of Medicine, 1994;87: 343-349.
  2. Endemic Melioidosis in Tropical Northern Australia: A 10-Year Prospective Study and Review of the Literature.  Bart J Currie, Dale A Fisher, Diane M Howard et al. Clin Infect Dis 2000;31:981-986
  3. Hospital Care for Aboriginal and Torres Strait Islanders: Appropriateness and decision-making.  Dale Fisher, Tarun Weeramanthri; Editorial Med J Aust 2002; 176: 49-50The Bali Bombings of October 12, 2002:
  4. The Bali Bombings of October 12, 2002: Lessons in Disaster Management for Physicians. Dale Fisher, James Burrow. Int Med J 2003; 33: 125-126
  5. Atypical presentations of SARS. Dale A Fisher, Tow-Keang Lim, Yean-Teng Lim, Kamaljit S Singh, Paul A Tambyah. The Lancet 17 May 2003. Vol. 361; P1740.
  6. Preventing local transmission of SARS: lessons from Singapore. Dale A Fisher, Madeleine H L Chew, Yean-Teng Lim and Paul A Tambyah. Published online ahead of print, MJA 19 May 2003. http://www.mja.com.au/public/rop/fis10245_fm.html
  7. Risk Factors for Nephrotoxicity associated with Continuous Vancomycin Infusion in Outpatient Parenteral Antibiotic Therapy. Ingram, Paul; Lye, David; Tambyah, Paul; Goh, Wei; Tam, Vincent; Fisher, Dale. Journal of Antimicrobial Chemotherapy (2008) 62, 168-171.Dengue management; Practical and safe hospital-based outpatient care. Paul R. Ingram, Malcolm Mahadevan, Dale A. Fisher. Trans R Soc Trop Med Hyg (2009) 103, 203-205.
  8. A Cost Analysis of Outpatient Parenteral Antibiotic Therapy (OPAT): An Asian Perspective. Candice Yong, Dale A. Fisher, Grant E. Sklar, Shu-Chuen Li. International Journal of Antimicrobial Agents; 33:1; Jan 2009, pp46-51
  9. Methicillin Resistant Staphylococcus aureus Control in Singapore - Moving Forward. Lynette Pereira, Dale Fisher. Ann Acad Med Singapore 2008;37:891-6.

Teaching Hand Hygiene to Medical Students using a Hands-On Approach. Dale Fisher; Lynette Pereira, Toon Mae Ng; Krista Patlovich, Felicia Teo, Li Yang Hsu; Journal of Hosp Infection; 76:1, Sept 2010, p 86-87